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pentobarbital will lower the extent or result of ripretinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. pentobarbital will minimize the level or effect of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. pentobarbital will lessen the level or outcome of lonafarnib by affecting hepatic/intestinal e